If you're going to say anything aloud to an empty room, please make sure the room is actually empty before you say it.
My friends left me alone in a room for about 10 minutes, which was fine until I started getting lonely. I thought they were all upstairs so I said aloud "Everybody betray me! I fed up with this world!" From the doorway, I hear "I'm right here, you know..." and one friend is standing right ouside the door. I still have no idea how to explain the fact that I was talking to myself (I showed him The Room clip, but I feel like it didn't justify talking to myself.
Anyway, just make sure you're really alone before you say things to yourself.
Stay classy.